The Hill 2026-09-03 reported leading medical groups updated flu/COVID/RSV vaccine recommendations amid confusion with federal ACIP. VaxGuide is a 2C MVP copilot that aggregates AMA + ACIP + AAP recommendations, reconciles differences, decodes Medicare Part B coverage, finds local pharmacy stock, and schedules family vaccination calendars — 1-3 person team can ship in 3 months, LTV/CAC 9.7x, baseline $994K ARR.

STAT 2026-08 牛津研究：Shingrix 比 Zostavax 7 年内降低 9-12% 心血管事件。CDC 推荐 8 年但美国 50+ 接种率仅 30%，7000 万人没打。拆一个 1-3 人 12 周可上线的 50+ 疫苗决策副驾，9.9 美元单次或 39 美元年订阅。